Ever since I began listening to podcasts I have been using iTunes, but now I have begun to try out two other clients: Juice and gPodder. Juice was the first one I tried, since it was the first one I'd hear about when alternatives to iTunes were discussed. Yet, I prefer gPodder as it is more easy to use. I didn't have to search for elementary functions such as adding subscriptions and initiating download. I also very much appreciated what happened upon importing an OPML file with loads of subscriptions: gPodder allowed me to check which podcasts on the list I wished to add. Note that gPodder also knows to communicate (in principle) with iPod.
Another option for podcatching is to go on-line. In stead of having a local client, one can setup a personal page with your podcasts. This allows you to access the same podcast collection from different computers, which would be ideal for users who use more than one computer to connect their player to. Such service is given at Odeo and Podnova. At Odeo I set up an account and found the site ot be slow and the procedure faulty and bothersome. The whole idea of having to manage yet another profile (in addition to Facebook, Twitter, Blogger, StumbleUpon, The Podcast Parlor etc etc etc) bothers ma and I was charmed by the fast, simple and anonymous solution at Podtopia: just enter the feed and there you go. But then: how much better is that than just directly downloading from the feed or the podcast's website?
More instructions:
Useful tools for podcast listeners,
Devising your own podcast feed - Huffduffer,
Suggestion for the advanced podcast listener,
What is RSS - Read Anne is a Man automatically.